Samuel Skelton - The Church's first pastor (1629-1634).
Francis Higginson - The author of the Church's Covenant and its first teacher (1629-1630)
Roger Williams - Founder of the First Baptist Church in America; third minister of this church in 1635.
Hugh Peter - The Church's fourth minister (1636-1641) return to England and became chaplain to Oliver Cromwell and was hanged, drawn and quartered for complicity in the death of King Charles I.
Rebecca Nurse & Giles Cory - Two of the victims of the witchcraft hysteria of 1692, were members of this Church.
Other notables include:
Nathaniel Hawthorne - And the Hawthorne family
Jones Very - Transcendentalist
Lincoln F. Bingham - Chief Justice of the Supreme Court of Massachusetts
Arthur Foote - Composer
Edward Sylvester Morse - Biologist and authority on Japanese culture
Nathaniel Peabody - Father of the Peabody sisters: Sophia Peabody Hawthorne, Mary Peabody Mann, and Elizabeth Palmer Peabody.
Leverett Saltonstal - lFirst mayor of Salem
Charles Dexter Cleveland - American Consul at Cardiff
Henry K. Oliver - Organist and composer
Elizabeth Peabody - Author, editor, publisher, educator, founder of American kindergartens,
Mary Peabody Mann - Educator, author, wife of Horace Mann
Sophia Amelia Peabody Hawthorne - Artist, author, educator, wife of Nathaniel Hawthorne
Susan Burley - Literary patron (including Nathaniel Hawthorne's),
salon/"Conversations" hostess, Transcendentalist